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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '284b45272981a49f67523e957c879932268de1e2b8e37c6e41854d0f5133f2c1' 
  AND token = 'IomuJBSKaZHaW1UR76P2ER0RcbDUhhWWT0UI4RgOwYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}