SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cb3e9f3b5f18309820b9a69785b84fc08060595441d49c9d8afb012a749f262' 
  AND token = '7mPulQLP0wLPx+E7aMxX2SBpEkFfpIzo/Y+4I0T+tSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00063

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}