SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6619203cb185a33073e27323d948a6d1c9c59eafb149745f32792feddeb2bd50' 
  AND token = 'U4GjHWr+sd+Sxi2eThezF5hoF2yWx1pmXbNp25/CQ2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00076

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}