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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78ea577488b1f1341f66333a41eb8380b52a1161b1e06ade46ee1146c85ef479' 
  AND token = 'uRw9smCGRljMAgSVc0+xHsBz91dMJ+GN7qfb25Ccyy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}