SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53939d859fa874f1025f81736625e9d5da3e1e604815b5112eff15b068cc3315' 
  AND token = 'ZzkSeH2LFgOHSxbniYMpD5la5NytsEZrJWEfeHrO0Nc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}