SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48da0ce9e0b83b7b1e62d7e35f09c909436253be7e767b9ca6448bc044ba286d' 
  AND token = 'esquHIfy0uogCbaekUmRf/X5KettXNNGygF91TflodA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}