SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fbcec5dc823cbea3a7396bb144e01ea0ed5de097c77dcbaed014b7e929e9b983' 
  AND token = '1f0RoiXP3b+VH1AiNIWkVf2E2t3CZKRwzGpr+vUZaY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00078

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}