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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4fef3a96314402daa790ac1e69d111fe3b4eff44002eec082121e6da8e6e4bc' 
  AND token = '65yJtXO3YU0fx4X74WoTx695WCZFH38/voHyBlzZtQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}