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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f6dc2960f614dab15b5eb19fd640df211ebb3ac516ec63830012029d1b5c57a' 
  AND token = '+QcDx6t6175PVdiJL0cbVo0dYDeIX6+w0vlk5O8d2Gc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}