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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa4aba4873c3f5da7158f6562c4205e2c5c8a8c035ee13966fcc0a0053378e53' 
  AND token = 'LCnuYm/fA6LGRqaFSL4v8fDGPn7E4G5x7G4pjnqrWM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}