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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '572725282d3a426561f7d6adb52c6d6a3988b38298c0d15adb510895ec4ac3d0' 
  AND token = 'ntETpXyUC6BL3ddlrsiIoH7VBXYjpMXDxBC3rddJVyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}