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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '192e77f51963fbfc3e42eb665e8bc84a90f42c9287c5684228885d4a5e2a61a6' 
  AND token = '6ab+ifa3PNoCOLYUUVy0Rg3W+49nFqLBJcKIlpLm53A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}