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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1abba3267644894d66557cb154dd3bdb9db49886071df7fd0ac7862679989268' 
  AND token = 'LPMmwTNQPQJkNo7gV2cswHW+bU09B7Gx7HuZbLbTqaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}