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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c33b06a13fa5e06fbcb0b8369d4a434e0b8f1ae38bf7ebddd7e702e9653fbd6' 
  AND token = 'zB/4mCCBXKAGLs8k/K+8IyUOnY1o/+l9cs0CZC8whbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}