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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3547f5b0395cbc7e71a1d1a8c2eb92bf145031a9100dd23adc82e137afd52d52' 
  AND token = 'pOKA/WtGpoDtFnFT5p2/e/RGDahe0Kc8qPSrQftCnYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}