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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '333cac741df84d9b30c8042dada5f069aab5c6678b57f9a8b28da328be12efcd' 
  AND token = '++r0y9tezkGbT7VbRt43Hyknj7CmLvtH20CkGqRn8Ic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}