SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da611e0bdf44545b894bf1c6539dfba7580d04307c6915ab45a1e8cf2fef7645' 
  AND token = 'Jj9KNzO6FzOh1AZfV8usdaRKE47EMTpVhB8ClJ3yKQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}