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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '800aeefdf8407e5346e2dbd6f55d16ee6d28541a5c15840bcf219a0da2254e45' 
  AND token = 'uQTb1NsQZwCKr95QHohtGn1Cy3gOmF3U/DZiSacTP74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}