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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8478fcb07712a07995b63a5cb9ffd350627d6061e78b6082c7ae0d47cbd49c2' 
  AND token = 'Io6AfUFYskxTe+rjWEt2GeCvUe0EEmzmMhYePzktqrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}