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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '805cc33b4a39e80e9978e4742d280c09f1b7f80ae642df3a5cc835a4e8d29484' 
  AND token = 'lKexgTx3yjCVKNcjdUyWy+FOLJGG7rIvcPuYtLs7P3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}