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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e87164c5422f65e4836ce37345a61e6bd79bc5eb93260df99d89d605e4dba9c1' 
  AND token = 'fIFy1Z/fKFam3xyPonWb+HDLGk43Sit/KuO2wNAo/Uc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}