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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f36c8504ca3f61a7386c2cc8e3b445448b645bf0f5012e28a2a820b152ee466' 
  AND token = 'XCuBlDTfnA/NAWnv312VNZJq5F7qty+CCwsJxFW8cRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}