SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4312aa22fc5cafa9126e75e217e115836cbcfb6d92ac31db8e665e8281cb14bb' 
  AND token = 'J+sraz5YIFaaAuy3IHQezF9m/C0E8A9rtw58baFRfFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}