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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '408ff910bcca64e4e1dce5bd434530e6a1b147103ae523ee0d63e49995f9e628' 
  AND token = 'PvUVVhliREXDKPR74PpWu1Od8Y9Z5bT+BBBoPQqsCCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}