SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a0fac2c10270aaa30600e62b72e6b1a34249dceb8a838b5bb55b9293644596e' 
  AND token = 'iVO/htbEHIxkE0HAjrv+ruGDkoqhF1vOFy4wdMKSUJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}