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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2afe5745186839808ecc77febb1af271e4b5f874ff771bcdaec64db96aec8f9' 
  AND token = '3I+ZAnCpxy/xRMLTwJ9kYA4lsxILs/uSDHpuiT1yCCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}