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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53aced63a2b99df5317d5750b3f53c6cb1bff77e73d67ea936bda0ff4f234c78' 
  AND token = 'DGcQfXUiDSqMjy7UWAfyySRttW0zZ5xnCARpNtLkyzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}