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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf8ed3d8e8114137d8720325a4d6fd448719478889813b98f9c0c05447bf750f' 
  AND token = 't+QUi/4GrmySL/TZ51hcYhBtdkgiURV3kAen7O1gpOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}