SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd66325dcb1be51c80113faa43d8ee56fb324042f4dd0c8e08ae275f4167b6344' 
  AND token = 'Ieus5omf2n85CfGX5yIapk6gpDuD2700XtRe6Tzbf1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}