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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10a2b5b1f4c10addccfcdafa9e2f3778888c878e06f497b861ef4cb303b99119' 
  AND token = 'pQzJt3vZbyA6JhWoS05/OqCFnhI14ZtTQh10/kpM0tM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}