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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '536adf6a6888a991a96d149b66636193b16f6f032f086a9ca5d096e4743e6ba3' 
  AND token = 'LFZdD1RNd9rl+8WLc0Eb+xl364Fuc9ZgNfijUSnI9yI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}