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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efdf0f6354b2582907af2a910a0b6afc2eeec11b40fa092b57e0be9c0bb36abd' 
  AND token = 'OxwYVfOB6e6IuILAp6jtIm9lNQvBg21G04zqQED66Q8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}