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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c78024bb33b9f3db276f49fd3c5fa24094d018866562c5eeccf33ed71f86aa2' 
  AND token = 'M8Aim9gvpNyHdwB1/VnEPum2our1XnCMtG2ZVuG7098=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}