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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '535380c3c7da73e35cea3250e9d6e9a0a30820b3d55d59da30880a6365dcb785' 
  AND token = 'nnoRIUbvMTpihhudL2msnqrPTgL9D21T5C7uyA75Ub4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}