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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a9e9fb2c95f8ad26347ef2a6cf67931fb5ac69539e0ff5d52539d600b49c323' 
  AND token = 'BCOoRyVXpRF2fKC8KKXszzQ+T26Xe7HEGRQDGIlDG2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00074

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}