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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49e095f723c2c02df682d3196c89d283348d9baaba9920e69ec13235cf874b03' 
  AND token = 'eWSUXYd9ThVr6OQ1N1PCjesz4xpMVbeZGN44v2QIiBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}