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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18d3fc356ac52a7a29deca0ae41179346c3c99074f4a14c85052433f6a6ae01e' 
  AND token = 'GUIyT0FK1VT/7ZqxKQOWqpWpkKvIPRTfANTzoldKf0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00060

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}