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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb78c31bf81a445e0b1a20b980f6992d31fe3e2b0c4f3417c220d63040913b5c' 
  AND token = 'ddxa780BSg32fqEUm3jn8zCDohF1kdgiS/diDlK5LW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00078

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}