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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ddb3bfe95e43062c5d928557193f70d9fb0c11673dd8e3c633ff35badb20891' 
  AND token = '4EcrgzEU+MSiepvZssHUFohrkn1YAnu/x0f/TmNgrhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}