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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f4000618e9d9d00f5b803661467f33098371ac38d6b9fdd55e5e087fee32268' 
  AND token = 'LjgpJbaWhLj+aEAh8HfbW0F/VHt1f5ud87xwvQvXMsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}