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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '954654e83010d9acc69c3371ca715c0e55ac264ae3dff06e74b1bc37824019e1' 
  AND token = '51FYJIJ3P4xUE5NfAJKT3C7A7KaTvZm5zxAGpJ+fQvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}