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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5a3c333808a8e8ebf52a72261ab9cf9aaa698939122b152937d3685b5330b7e' 
  AND token = '1KTMkkRgVTMVyQZHGCcs1jxlLo55R5LJQ/E3sYxEj2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}