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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aeadc3fff5342bd32eccb66731d6ebaa3e9037e72df080e33d582252b46abbaa' 
  AND token = 'T1+X3u8Ir2udGiRpTujS/UOEOSlheXWlM9sj4jcUJgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}