SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd481261b085a55cffee69ef2cecc5cf52ffc80a02415074a8770e3876e94ad58' 
  AND token = '/i//BB/k+ewoI6v/Nnc88vnix6ebbVno943ILE/oVII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}