SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df0ed6fe678c2991b442457ee39a414837193ad2fd397ac7e1999dc2db088e5d' 
  AND token = '0kHYGgjLZAJqxocMS1zcpCmo0OAEl6UZa+j+iZgZAto=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}