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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f14beda2fcf582218cd5a21f9e5107196246dd4af11f47a2306936f2b03c6eba' 
  AND token = 'yAS4R+lRrdf+1xWgv3bPgMuK9ydjdL5a6nsm3GSqZQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}