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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a15c0ee70161e47be8d464e9f014d10f2c937c8a31e4638732d8385f326f8027' 
  AND token = '5GOIuzUVtfqrEt59ZdfM7YiUcs2OTA/83u0Oe/Gz1Tc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00069

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}