SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53704323270e2e919c47445b7318c79e9bab9e9925eeb243f1920b34411a61df' 
  AND token = 'hvOCFlK6HLsFVGsRvb3kBosPLaRygBFymld1miaflcg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}