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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cde82c78772f1f4100503e10a53f1b47aca7d1729bcbbe98c80c3d8fec99fd58' 
  AND token = 'RS7TXWwaCPpNWkaWoNXCzoUG0pJ4sb35FyXKYQwC5RQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}