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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f21c3e3d9cadc743e45204a49c77d2706231cad4db46dc9e857a3e855424598' 
  AND token = 'cE52mDU/q049BI4rwaqhK8vYKt0yPCdVI9mPYNUqxeQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}